The impact of aging for increasing overactive bladder, approaching to new therapeutic technique.

2012 Fiscal Year Final Research Report

• Project/Area Number: 22650122
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Single-year Grants
• Research Field: Rehabilitation science/Welfare engineering
• Research Institution: Tohoku University
• Principal Investigator: NAKAGAWA Haruo 東北大学, 大学院・医学系研究科, 准教授 (80333574)
• Co-Investigator(Kenkyū-buntansha): KAIHO Yasuhiro 東北大学, 病院, 講師 (30447130)
• Project Period (FY): 2010 – 2012
• Keywords: 加齢 / 過活動膀胱 / 血流 / 排尿障害 / 神経調整 / 高齢者

Research Abstract

The prevalence of overactive bladder increases according to aging. In our epidemiological study, the risk factors of overactive bladder were depressive state and the disease relevant to arteriosclerosis in the elderly population. In the mice, pelvic blood flow promptly increases after electrical stimulation. These results suggest that one of the mechanisms of increasing in the overactive bladder by aging was the morbidityof central nervous system and the pelvic blood flow.

Research Products

• [Journal Article] Risk factors for overactive bladder in the elderly population: A community-based study with face-to-face interview (2011)
  • Author(s): Ikeda Y, Nakagawa H, Ohmori- Matsuda K, Hozawa A, Masamune Y, Nishino Y, Kuriyama S, Ohnuma T, Tsuji I, Arai Y.
  • Journal Title: Int J Urol Volume: 18(3) Pages: 212-8
  • DOI: doi:10.1111/j.1442-2042.2010.02696.x.
  • Peer Reviewed
• [Journal Article] 男性尿失禁の現状 (2011)
  • Author(s): 中川晴夫、海法康裕、荒井陽一
  • Journal Title: 臨床と研究 Volume: Vol.88 No.10 Pages: 103-106
• [Journal Article] 【ケアマネージャーに必要な疾患の知識と活用】過活動膀胱(OAB) (2011)
  • Author(s): 中川晴夫
  • Journal Title: 達人ケアマネ Volume: Vol.6 No.1 Pages: 66-71
• [Journal Article] 【排尿障害の私の治療2 OAB・間質性膀胱炎】薬剤抵抗性過活動膀胱に対する仙骨表面治療的電気刺激治療 (2011)
  • Author(s): 中川晴夫
  • Journal Title: 排尿障害プラクティス Volume: Vol.19 No.3 Pages: 216-220
• [Journal Article] 薬の効かない頻尿や尿失禁 (2010)
  • Author(s): 中川晴夫
  • Journal Title: 仙台っこ(タウン誌) Volume: 2010年4・5月号 Pages: 24-24
• [Journal Article] 脳磁図 (2010)
  • Author(s): 松下真史,中川晴夫,中里信和,菅野彰剛,海法康裕,川守田直樹,荒井陽一
  • Journal Title: 臨床検査 Volume: 54巻7号 Pages: 819-822
• [Journal Article] 【夜間頻尿Update:もう外来で困らない】介護施設における夜間頻尿の実態 (2010)
  • Author(s): 今西里佳,中川晴夫,松本香好美,荒井陽一
  • Journal Title: UrologyView Volume: 8巻3号 Pages: 60-63
• [Journal Article] Impact of nocturia on bone fracture and mortality in older individuals: a Japanese longitudinal cohort study (2010)
  • Author(s): Nakagawa H, Niu K, Hozawa A, Ikeda Y, Kaiho Y, Ohmori-Matsuda K, Nakaya N, Kuriyama S, Ebihara S, Nagatomi R, Tsuji I, Arai Y
  • Journal Title: J Urol Volume: 184(4) Pages: 1413-8
  • DOI: doi:10.1016/j.juro.2010.05.093.
  • Peer Reviewed
• [Journal Article] Impact of sacral surface therapeutic electrical stimulation on early recovery of urinary continence after radical retropubic prostatectomy: a pilot study (2010)
  • Author(s): Nakagawa H, Kaiho Y, Namiki S, Ishidoya S, Saito S, Arai Y.
  • Journal Title: Adv Urol. Volume 2010 Volume: Article ID 102751 Pages: 5
  • DOI: doi:10.1155/2010/102751.
  • Peer Reviewed
• [Presentation] シンポジウム:どうする日本のデバイスラグ (2012)
  • Author(s): 中川晴夫、海法康裕、荒井陽一
  • Organizer: 第26回日本泌尿器内視鏡学会総会
  • Place of Presentation: 仙台市
  • Year and Date: 2012-11-23
• [Presentation] シンポジウム:難治性下部尿路機能障害に挑む「電気刺激療法」 (2012)
  • Author(s): 中川晴夫、海法康裕、半田康信、荒井陽一
  • Organizer: 第100回日本泌尿器科学会総会
  • Place of Presentation: 横浜市
  • Year and Date: 2012-04-21
• [Presentation] Overactive Bladder and Sacral Surface Therapeutic Electrical Stimulation. (2011)
  • Author(s): Nakagawa H
  • Organizer: Healthcare InnovationForum 2011 (Keynote Lecture)
  • Place of Presentation: Singapore, Singapore
  • Year and Date: 2011-10-22
• [Presentation] Nighttime Storage Symptoms In Female Stroke Residents Staying At A Residential Facility (2011)
  • Author(s): Imanishi R, Nakagawa H, Matsumoto K, Arai Y, Kohzuki M
  • Organizer: 6^<th> World Congress of The International Society of Physical and Rehabilitation Medicine
  • Place of Presentation: San Juan, Puerto Rico
  • Year and Date: 2011-06-15
• [Presentation] 会長指定シンポジウム:「末梢感覚入力によるニューロモデュレーション:泌尿器科分野:排尿障害」 (2011)
  • Author(s): 中川晴夫、海法康裕、半田康信、荒井陽一
  • Organizer: 第25回日本ニューロモデュレーション学会
  • Place of Presentation: 東京都
  • Year and Date: 2011-05-21
• [Presentation] Topic: Incontinence and the Use of Prosthetics to Enhance Urinary Control (2011)
  • Author(s): Nakagawa H, Kaiho Y, Arai Y.
  • Organizer: American Urological Association Annual Meeting Washington D.C. USA, Global Perspectives in Urology Forum
  • Place of Presentation: Panelist
  • Year and Date: 2011-05-18
• [Presentation] Joint session of the European Association of Urology (EAU) and the Japanese Urological Association (JUA) (Invited Speaker) Treatment for post- prostatectomy incontinence (2011)
  • Author(s): Nakagawa H, Kaiho Y, Arai Y.
  • Organizer: 26^<th> Annual EAU Congress
  • Place of Presentation: Vienna Austria
  • Year and Date: 2011-03-18
• [Presentation] パネルディスカッション:「高齢者の夜間頻尿をめぐる諸問題」 (2010)
  • Author(s): 中川晴夫
  • Organizer: 24時間在宅ケア研究会横浜フォーラム
  • Place of Presentation: 横浜市
  • Year and Date: 2010-12-16
• [Presentation] Investigation of nighttime storage symptoms of female residents with stroke in a geriatric health services facility (2010)
  • Author(s): Imanishi R, Nakagawa H, Matsumoto K, Awaji S, Nabekura M, Tanno O, Kaiho Y, Matsushita M, Arai Y, Kohzuki M
  • Organizer: International Continence Society 39th Annual Meeting
  • Place of Presentation: Toronto CANADA
  • Year and Date: 2010-08-28
• [Presentation] シンポジウム:「過活動膀胱の基礎と臨床」過活動膀胱の疫学とリスクファクター (2010)
  • Author(s): 中川晴夫、池田義弘、海法康裕、荒井陽一
  • Organizer: 第52回日本平滑筋学会総会
  • Place of Presentation: 仙台市
  • Year and Date: 2010-07-01
• [Book] 【過活動膀胱診療を考える】 Neuromodulation 最前線 Progress in Medicine 32 (2012)
  • Author(s): 中川晴夫 、海法康 裕 、泉秀明、荒井陽一
  • Total Pages: 875-878
  • Publisher: ライフサ イエンス社
• [Remarks] (1)沖縄タイムズ16面「夜間頻尿生活の質低下」2012.5.2 新聞報道
• [Remarks] (2)京都新聞17面「危険です夜間頻尿;転倒や生活の質低下」2012.4.10 新聞報道
• [Remarks] (3)佐賀新聞29面「高齢者に多い夜間頻尿不眠、生存率低下も」2012.3.28 新聞報道
• [Remarks] (4)徳島新聞15面「夜間頻尿で生存率低下睡眠障害や転倒・骨折の恐れ」2012.3.25 新聞報道
• [Remarks] (5)福島民友15面「夜間頻尿で生存率低下高齢者注意」2012 新聞報道
• [Remarks] (6)日本海新聞15面「夜間頻尿が寿命に影響」2012.3.22 新聞報道
• [Remarks] (7)南日本新聞15面「夜間頻尿寿命に影響、病気の初期の可能性も」2012.3.20 新聞報道
• [Remarks] (8)愛媛新聞20面「夜間頻尿危険サイン」2012.3.20 新聞報道
• [Remarks] (9)神奈川新聞12面「夜間頻尿は重大な問題:生活の質と生存率低下」2012.3.18 新聞報道
• [Remarks] (10)読売新聞20面いきいき健康生活「夜間頻尿、水分調節を」2012.1.13 新聞報道
• [Remarks] (11)朝日新聞26面「夜のおしっこ多いと危険?高齢者死亡率上がる傾向」2010.5.2 新聞報道
• [Remarks] (12)朝日新聞家庭面「元気のひけつ気を付けよう,夜中のおしっこ」2010.4.3 新聞報道
• [Remarks] (13)日本経済新聞14面健康「夜間頻尿年のせい?」2010.1.17 新聞報道