2011 Fiscal Year Final Research Report
Development of in vivo electroporation method for miRNA functional analysis in brain tumor development.
| Project/Area Number |
22650225
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Carcinogenesis
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| Research Institution | 公益財団法人がん研究会 (2011)
Japanese Foundation For Cancer Research (2010) |
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Principal Investigator |
SUGITANI Yoshinobu 公益財団法人がん研究会, ゲノムセンター, 研究員 (80360569)
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| Project Period (FY) |
2010 – 2011
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| Keywords | 神経前駆細胞 / 多段階発癌 / miRNA / 脳腫瘍 / 細胞分化 / Shhシグナル / 遺伝子発現制御 / in vivoエレクトロポレーション |
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| Research Abstract |
Development and application of new in vivo electroporation method, which is combined with transposon & insulator-based plasmid vector system, opened the door to elucidate that miRNAs are involved in shh-associated medulloblastoma formation.
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