2011 Fiscal Year Final Research Report
Construction of label-free biochips using anomalous reflection of gold
| Project/Area Number |
22651047
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Nanomaterials/Nanobioscience
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| Research Institution | Tokyo Institute of Technology |
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Principal Investigator |
MIHARA Hisakazu 東京工業大学, 大学院・生命理工学研究科, 教授 (30183966)
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| Project Period (FY) |
2010 – 2011
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| Keywords | バイオチップ / 金基板 / 反射法 / 非標識 / ペプチド |
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| Research Abstract |
A efficient label-free detection method is desired to improve the technology of biochips including protein microarray. In this study, the novel label-free detection method using anomalous reflection of gold(AR) was developed. The AR method is highly sensitive and easy to miniaturize so as to apply it to biochips detecting various peptide and protein interactions in a high-throughput manner.
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