2011 Fiscal Year Final Research Report
Study on the absorpt i on of b i oact i ye pept i des depend i ng on the onset of diseases
| Project/Area Number |
22658044
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Food science
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| Research Institution | Kyushu University |
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Principal Investigator |
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| Project Period (FY) |
2010 – 2011
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| Keywords | 食品機能 |
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| Research Abstract |
In this study, in order to elucidate effect of the onset of diseases on absorption of bioactive small peptides, a stable isotope labeling LCMRM-MS/MS method forsuccessive determination of peptides in rat blood was primarily developed. By using this newly developed assay method, ca. 2-times higher absorption of one of dipeptides, Trp-His in SHRs was observed for the first time, compared to normal rats.
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