2011 Fiscal Year Final Research Report
Establishment of pluripotent stem cells from trophoblast stem cells
| Project/Area Number |
22658084
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Applied animal science
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| Research Institution | Tokyo University of Agriculture |
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Principal Investigator |
OGAWA Hidehiko 東京農業大学, 応用生物科学部, 准教授 (20339089)
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| Co-Investigator(Kenkyū-buntansha) |
KONO Tomohiro 東京農業大学, 応用生物科学部, 教授 (80153485)
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| Project Period (FY) |
2010 – 2011
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| Keywords | 発生・分化 / 再生医療 / 核移植 / リプログラミング |
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| Research Abstract |
To identify whether trophoblast stem cells regain the pluripotency, the developmental ability of the reconstructed embryos transferred trophoblast stem cells as donors has been examined. Though many those reconstructed embryos were arrested at 2 cell stage, some embryos developed into blastocysts and formed inner cell mass that expressed Oct3/4.These results suggest that trophoblast stem cells have a potential to form the pluripotent cells by using the nuclear transfer.
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Research Products
(1 results)
