2011 Fiscal Year Final Research Report
Effects of chronic morphine treatment on angiogenesis
Project/Area Number |
22659279
|
Research Category |
Grant-in-Aid for Challenging Exploratory Research
|
Allocation Type | Single-year Grants |
Research Field |
Anesthesiology/Resuscitation studies
|
Research Institution | Shinshu University |
Principal Investigator |
|
Project Period (FY) |
2010 – 2011
|
Keywords | 疼痛管理学 |
Research Abstract |
Chronic treatment of morphine at low doses(0. 1-3 mg/kg/day) attenuated the growth of Lewis lung carcinoma(LLC) in C57BL/6 mice. However, higher dose(10mg/kg/day) of morphine does not affect LLC growth. These results suggest that effects of chronic morphine treatment on growth of LLC may be biphasic alteration.
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Research Products
(13 results)