2012 Fiscal Year Final Research Report
Establishment of small scale bone augmentation without the reflection of periosteum
| Project/Area Number |
22659348
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Prosthetic dentistry
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| Research Institution | Niigata University |
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Principal Investigator |
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| Research Collaborator |
HAIDARIAN Nasri Mohammad Edris 新潟大学, 大学院, 学生
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| Project Period (FY) |
2010 – 2012
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| Keywords | 歯科補綴学一般 |
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| Research Abstract |
To establish a new technique of small scale bone augmentation for dental implant application without the reflection of periosteum, animal experiments were carried out using mixtures of Biopex-R (α-TCP) and several cytokines. Biopex-R and BMP-2, EGF, FGF-2, PDGF were mixed respectively and applied under rat calvarial periosteum using 18G needle. As a result of histological investigations, mixtures ofBiopex-R and BMP-2, EGF, PDGF showed better bone formation in comparison to Biopex-Ronly.
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