2011 Fiscal Year Final Research Report
Selection of osteogenic progenitor cells in gingival tissue
| Project/Area Number |
22659359
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Dental engineering/Regenerative dentistry
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| Research Institution | Nagasaki University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
SUMITA Yoshinori 長崎大学, 大学院・医歯薬学総合研究科, 助教 (50456654)
SUEHIRO Fumio 長崎大学, 大学院・医歯薬学総合研究科, 助教 (40524781)
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| Project Period (FY) |
2010 – 2011
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| Keywords | 歯肉幹細胞 / 骨再生 / 歯槽骨再生 |
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| Research Abstract |
The purpose of this project was to discover the method to collect osteogenic cells in gingival tissues. Phenotype of human gingival cells was heterogenic, and we could not uniformly divide them by MACS. Among tested antibodies, anti-CD166 induced one of gingival cells and mesenchymal stem cells as well. Anti-CD166 might bind to the receptor of the cells which have the ability for osteogenic differentiation. MACS might show additive role for selection of these osteogenic progenitor cells.
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