2012 Fiscal Year Final Research Report
COMPREHENSIVE HOME CARE OF CHILDREN WITH FOP (Fibrodysplasia Ossificans Progressiva)
| Project/Area Number |
22659409
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Lifelong developmental nursing
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| Research Institution | Shiga University of Medical Science |
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Principal Investigator |
KUWATA Hiromi 滋賀医科大学, 医学部, 教授 (70324316)
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| Co-Investigator(Kenkyū-buntansha) |
SAKAMOTO Yutaka 岐阜大学, 教育学研究科, 准教授 (20310039)
SHIRASAKA Maki 滋賀医科大学, 医学部, 助教 (40378443)
KOSHIDA Shigeki 滋賀医科大学, 医学部, 特任講師 (70372547)
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| Co-Investigator(Renkei-kenkyūsha) |
KUWATA Kazuo 岐阜大学, 大学院・連合創薬医療情報研究科, 教授 (00170142)
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| Research Collaborator |
SOGA Hiroyoshi 滋賀医科大学, 医学部, 助教 (40614045)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 小児看護学 / 創薬 |
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| Research Abstract |
FOP is a rare disease in which muscles in the body gradually replaced with bones. The aim of this study isto investigate the actual situation of home care for FOP patients and to consider the possible nursing home care for FOP patients. FOP patients kept moving in mind possible when they could move in in their childhood. FOP children are now dependent on their families, they hope to live their own life in future. Most of mothers experienced to promote their children’s independences. Using logical drug design method, we searched compounds, especially nutrienrs which can interact with ACVR1 mutation region, around H206, and found several compounds including masoprocol and enoximone as possible candidates.
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