2013 Fiscal Year Final Research Report
Visualization techniques for electrokinetic flow dynamics in confined nanospace
| Project/Area Number |
22686021
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| Research Category |
Grant-in-Aid for Young Scientists (A)
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| Allocation Type | Single-year Grants |
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| Research Field |
Fluid engineering
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| Research Institution | Kyoto University (2012-2013)
Osaka University (2010-2011) |
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Principal Investigator |
SHINTAKU Hirofumi 京都大学, 工学(系)研究科(研究院), 助教 (80448050)
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| Project Period (FY) |
2010-04-01 – 2014-03-31
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| Keywords | 界面動電現象 / ナノ制限空間 / 生体高分子 / 1分子計測 / MEMS流体 |
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| Research Abstract |
In this study, we have developed measurement techniques for electrokinetic flow dynamics in nano-confiend spaces and applied our techniques to develop novel techniques for the analyses of biomacromolecules. We first investigated electrophoretic flows of biomacromolecules in nano channels and nano pores, and found the nano-confinement decreases the mobility of the biomacromolecules. We second extended our measurement technique to investigate unsteady ionic flows in the cell electroporation with micro-pores. We lastly proposed a technique for simultaneously extracting, separating, and quantifying RNA and DNA from single cells by integrating on-chip electroporation and isotachophoresis.
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[Remarks] 2011年8月1日 平成23年 大阪大学功績賞(新宅博文)
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[Remarks] 2010年4月23日日本機械学会奨励賞(研究), MEMS 流体デバイスによる界面現象の制御と計測に関する研究(新宅博文)
