2012 Fiscal Year Final Research Report
The role of membrane nanotubes in the immune system
Project/Area Number |
22689017
|
Research Category |
Grant-in-Aid for Young Scientists (A)
|
Allocation Type | Single-year Grants |
Research Field |
Immunology
|
Research Institution | The University of Tokyo (2012) The Institute of Physical and Chemical Research (2010-2011) |
Principal Investigator |
HASE Koji 東京大学, 医科学研究所, 特任教授 (20359714)
|
Project Period (FY) |
2010 – 2012
|
Keywords | 粘膜免疫 |
Research Abstract |
Cell-to-cell communication is essential for the development and maintenance of multicellular organisms. The tunneling nanotube (TNT) is a recently recognized distinct type of intercellular communication device. We have recently shown that M-Sec (also called TNFaip2) is a key molecule for TNT formation. We also elucidated the molecular machinery of M-Sec-dependent TNT formation.
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Research Products
(12 results)