Distribution of dopamine receptors in the marmoset brain : a PET study

2011 Fiscal Year Final Research Report

• Project/Area Number: 22700340
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Neuroscience in general
• Research Institution: Kobe University
• Principal Investigator: TSUJIMOTO Satoshi 神戸大学, 大学院・人間発達環境学研究科, 准教授 (20539241)
• Research Collaborator: MINAMIMOTO Takafumi 独立行政法人放射線医学総合研究所, チームリーダー (23011006) ; NAGAI Yuji 独立行政法人放射線医学総合研究所, 研究員 (20415409)
• Project Period (FY): 2010 – 2011
• Keywords: 認知神経科学

Research Abstract

We assessed the distribution of dopamine receptors in the marmoset brain with a PET using radioactive ligand. We observed high binding potential of dopamine D1 and D2 receptors in the striatum. We also evaluated the biding potential in the cerebral cortex, and confirmed variations across cerebral areas. This study established the method for quantitative evaluation of dopamine in the marmoset brain, and provided the data to construct a database.

Research Products

• [Journal Article] Encoding goals but not abstract magnitude in the primate prefrontal cortex. (2012)
  • Author(s): Genovesio A, Tsujimoto S, and Wise SP
  • Journal Title: Neuron Volume: (印刷中)
  • DOI: DOI:10.1016/j.neuron.2012.02.023
  • Peer Reviewed
• [Journal Article] The prefrontal cortex and oculomotor delayed response : a reconsideration of the "mnemonic scotoma" (2012)
  • Author(s): Tsujimoto S and Postle BR
  • Journal Title: Journal of Cognitive Neuroscience Volume: 24 Pages: 627-635
  • Peer Reviewed
• [Journal Article] Modulation of neuromagnetic responses to face stimuli by preceding biographical information (2011)
  • Author(s): Tsujimoto S, Yokoyama T, Noguchi Y, Kita S, and Kakigi R
  • Journal Title: European Journal of Neuroscience Volume: 34 Pages: 2043-2053
  • Peer Reviewed
• [Journal Article] Frontal pole cortex : encoding ends at the end of the endbrain (2011)
  • Author(s): Tsujimoto S, Genovesio A, and Wise SP
  • Journal Title: Trends in Cognitive Sciences Volume: 15 Pages: 169-176
  • Peer Reviewed
• [Journal Article] Comparison of strategy signals in the dorsolateral and orbital prefrontal cortex (2011)
  • Author(s): Tsujimoto S, Genovesio A, and Wise SP
  • Journal Title: Journal of Neuroscience Volume: 31 Pages: 4583-4592
  • Peer Reviewed
• [Journal Article] Prefrontal cortex activity during the discrimination of relative distance (2011)
  • Author(s): Genovesio A, Tsujimoto S, and Wise SP
  • Journal Title: Journal of Neuroscience Volume: 31 Pages: 3968-3980
  • Peer Reviewed
• [Presentation] Influence of distraction on working memory and prefrontal cortex activity in children with ADHD (2012)
  • Author(s): Tsujimoto S, Yasumura A, Yamashita Y, Kaga M, Inagaki M
  • Organizer: Cognitive Neuroscience Society 2012 Meeting
  • Place of Presentation: Chicago, IL, USA
  • Year and Date: 2012-04-01
• [Presentation] Prefrontal neurocognitive function in children with and without ADHD(and monkeys) (2012)
  • Author(s): Tsujimoto S
  • Organizer: University of Wisconsin-Madison, Department of Neuroscience Seminar Series
  • Place of Presentation: Madison, WI, USA
  • Year and Date: 2012-03-28
• [Presentation] 前頭前野外側部のワーキングメモリ再考 (2012)
  • Author(s): 辻本悟史
  • Organizer: 生理学研究所研究会グローバルネットワークによる脳情報処理
  • Place of Presentation: 岡崎
  • Year and Date: 2012-01-07
• [Presentation] Comparison of prefrontal cortex activity in spatial and temporal discrimination tasks (2011)
  • Author(s): Genovesio A, Tsujimoto S, and Wise SP
  • Organizer: 41st Annual Meeting of Society for Neuroscience
  • Place of Presentation: Washington DC, USA
  • Year and Date: 2011-11-14
• [Presentation] どちらが長い?サルの前頭皮質における時間弁別のニューロン機構 (2010)
  • Author(s): 辻本悟史
  • Organizer: 第74回日本心理学会
  • Place of Presentation: 大阪
  • Year and Date: 2010-09-22
• [Book] 発達脳科学 (2012)
  • Author(s): 辻本悟史
  • Publisher: 培風館
• [Book] 脳と心の発達 (2011)
  • Author(s): 辻本悟史
  • Total Pages: 120-132
  • Publisher: 培風館
• [Remarks] アウトリーチ活動(講演)(1)辻本悟史「個性を生み出す脳」寺子屋セミナー, 2011年11月23日,岐阜アウトリーチ活動(講演)
• [Remarks] (2)辻本悟史「脳と心の健康」尼崎市養護教諭研究会, 2011年1月13日,尼崎アウトリーチ活動(講演)
• [Remarks] (3)辻本悟史「脳科学と教育について-脳と心の並列階層性-」加東市教育委員会学習指導研修, 2010年8月5日,加東アウトリーチ活動(講演)
• [Remarks]
  • URL: http://www2.kobe-u.ac.jp/~stlab/