Phylogenetic mechanisms of the neocortex

2011 Fiscal Year Final Research Report

• Project/Area Number: 22700370
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Nerve anatomy/Neuropathology
• Research Institution: Keio University
• Principal Investigator: TANAKA Daisuke 慶應義塾大学, 医学部, 助教 (90456921)
• Project Period (FY): 2010 – 2011
• Keywords: 大脳新皮質 / 進化 / 神経細胞移動

Research Abstract

An evolutionary change in the migratory ability of inhibitory interneurons that originate outside the neocortex was involved in the establishment of the neocortex by supplying inhibitory components to the network.

Research Products

• [Journal Article] Changes in cortical interneuron migration contribute to the evolution of the neocortex (2011)
  • Author(s): Tanaka DH, Oiwa R, Sasaki E and Nakajima K
  • Journal Title: Proc. Natl. Acad. Sci USA Volume: 108(19) Pages: 8015-8020
  • Peer Reviewed
• [Presentation] Evolutionary developmental basis in the adaptation of pallial GABAergic interneurons to mammalian layered neocortex (2010)
  • Author(s): Tanaka-Harada D, Oiwa R, Sasaki E and Nakajima K
  • Organizer: The 33th Annual Meeting of the Japan Neuroscience Society
  • Place of Presentation: Kobe, Japan
  • Year and Date: 20100902-04
• [Presentation] Critical evolutionary steps for pallial GABAergic interneurons to adapt to mammalian layered neocortex (2010)
  • Author(s): Tanaka-Harada D, Oiwa R, Sasaki E and Nakajima K
  • Organizer: The 43th Annual Meeting for the Japanese Society of Develomental Biologists
  • Place of Presentation: Kyoto, Japan
  • Year and Date: 20100620-23
• [Presentation] Migratory pathways of avian MGE-derived GABAergic interneurons in the mammalian neocortex : implications for the evolutional adaptation in GABAergic interneuron migration (2009)
  • Author(s): Tanaka DH and Nakajima K
  • Organizer: Construction and Reconstruction of the Brain
  • Place of Presentation: Awaji, Japan
  • Year and Date: 20091008-10
• [Presentation] Behavior of avian pallial GABAergic interneurons in the mammalian neocortex : implications for the evolutional adaptation to the neocortex in pallial GABAergic interneurons (2009)
  • Author(s): Tanaka DH and Nakajima K
  • Organizer: The 32th Annual Meeting of the Japan Neuroscience Society
  • Place of Presentation: Nagoya, Japan
  • Year and Date: 20090916-18
• [Remarks] [報道関連](1) 2011年4月26日日刊工業新聞朝刊19面にて紹介
• [Remarks] (2) 2011年4月29日マイコミジャーナル(毎日コミュニケーションズ)にて紹介
  • URL: http://journal.mycom.co.jp/news/2011/04/29/007/index.html?route=blog
• [Remarks] (3) 2011年5月13日週刊科学新聞3面(科学技術総合欄)にて紹介
• [Remarks] (4) Newton 2011年8月号(6月25日発売)に紹介記事掲載(北京版、台湾版、韓国版にも掲載予定)
• [Remarks] [アウトリーチ活動] Tanaka DH, Guest, Science Cafe(WEcafe), Tokyo, Japan, 2011