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2011 Fiscal Year Final Research Report

Characterization of synaptic inputs to cerebellar globular cells

Research Project

  • PDF
Project/Area Number 22700423
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Neurophysiology and muscle physiology
Research InstitutionThe Institute of Physical and Chemical Research

Principal Investigator

HIRONO Moritoshi  独立行政法人理化学研究所, 運動学習制御研究チーム, 研究員 (30318836)

Project Period (FY) 2010 – 2011
Keywords小脳 / グロビュラー細胞 / ルガロ細胞 / プルキンエ細胞 / 抑制性介在ニューロン / 苔状線維 / セロトニン
Research Abstract

Cerebellar globular cells, a subgroup of Lugaro cells, have been identified morphologically. By using whole-cell patch-clamp recordings we found that globular cells received prominent IPSCs together with monosynaptic inputs from the axon collaterals of Purkinje cells. Additionally, globular cells likely received excitatory monosynaptic inputs through mossy fibers. Globular cells appear to integrate input and output signals of the cerebellar cortex.

  • Research Products

    (11 results)

All 2012 2011 2010 Other

All Journal Article (1 results) (of which Peer Reviewed: 1 results) Presentation (8 results) Book (1 results) Remarks (1 results)

  • [Journal Article] Cerebellar globular cells receive monoaminergic excitation and monosynaptic inhibition from Purkinje cells2012

    • Author(s)
      Hirono M, Saitow F, Kudo M, Suzuki H, Yanagawa Y, Yamada M, Nagao S, Konishi S, Obata K.
    • Journal Title

      PLoS ONE

      Volume: 7(1) Pages: e29663

    • Peer Reviewed
  • [Presentation] 小脳グロビュラー細胞へのGABA作動性シナプス伝達の薬理学的特性2012

    • Author(s)
      廣野守俊、工藤もゑこ、柳川右千夫、小西史朗、永雄総一、小幡邦彦
    • Organizer
      第89回日本生理学会大会
    • Place of Presentation
      長野県松本文化会館
    • Year and Date
      2012-03-29
  • [Presentation] Physiological characteristic of small inhibitory interneurons underneath the cerebellar Purkinje cell layer2011

    • Author(s)
      Hirono M, Saitow F, Kudo M, Suzuki H, Yanagawa Y, Yamada M, Nagao S, Konishi S, Obata K
    • Organizer
      The 4^<th> International symposium of the society for research on the cerebellum
    • Place of Presentation
      Tokyo, Japan
    • Year and Date
      2011-09-18
  • [Presentation] 小脳グロビュラー細胞へのシナプス入力の研究2011

    • Author(s)
      廣野守俊、齋藤文仁、工藤もゑこ、鈴木秀典、柳川右千夫、山田真久、永雄総一、小西史朗、小幡邦彦
    • Organizer
      第34回日本神経科学大会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2011-09-17
  • [Presentation] Cerebellar globular cells receive inhibitory synaptic transmission from Purkinje cells2011

    • Author(s)
      Hirono M
    • Organizer
      OIST international workshop "Molecular & structural organization of presynaptic function and plasticity"
    • Place of Presentation
      Okinawa, Japan
    • Year and Date
      2011-09-07
  • [Presentation] モノアミンにより発火する小脳グロビュラー細胞の役割2011

    • Author(s)
      廣野守俊、齋藤文仁、鈴木秀典、柳川右千夫、山田真久、永雄総一、小西史朗、小幡邦彦
    • Organizer
      第15回活性アミンに関するワークショップ
    • Place of Presentation
      徳島文理大学国際会議場
    • Year and Date
      2011-08-11
  • [Presentation] 小脳グロビュラー細胞へ入力するシナプス伝達の解析2011

    • Author(s)
      廣野守俊、齋藤文仁、工藤もゑこ、鈴木秀典、柳川右千夫、山田真久、永雄総一、小西史朗、小幡邦彦
    • Organizer
      第88回日本生理学会大会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2011-03-28
  • [Presentation] 小脳グロビュラー細胞へのシナプス入力の解析2010

    • Author(s)
      廣野守俊
    • Organizer
      生理研研究会「シナプス伝達の概念志向型研究」
    • Place of Presentation
      岡崎
    • Year and Date
      2010-12-07
  • [Presentation] 小脳プルキンエ細胞から強い抑制を受ける顆粒層小型抑制性介在ニューロンの解析2010

    • Author(s)
      廣野守俊、齋藤文仁、鈴木秀典、柳川右千夫、山田真久、小西史朗、小幡邦彦
    • Organizer
      第87回日本生理学会大会
    • Place of Presentation
      盛岡市
    • Year and Date
      2010-05-19
  • [Book] 多様なニューロンにより精緻化される小脳神経回路、[特集]小脳研究の課題、生体の科学2011

    • Author(s)
      廣野守俊
    • Total Pages
      292-297
  • [Remarks]

    • URL

      http://mlc.brain.riken.jp/index.html

URL: 

Published: 2013-07-31  

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