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2011 Fiscal Year Final Research Report

Development of bidirectional brain-machine interface using electrocorticogram to restore motor functions of arms for paralyzed patients

Research Project

  • PDF
Project/Area Number 22700435
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Fusional brain recording science
Research InstitutionOsaka University

Principal Investigator

YANAGISAWA Takufumi  大阪大学, 医学系・研究科, 特任研究員 (90533802)

Project Period (FY) 2010 – 2011
Keywordsブレインマシーンインターフェイス
Research Abstract

In this study, we have developed a bidirectional brain-machine interface to operate a prosthetic arm with tactile sensor using the electrocorticogram(ECoG) recorded by the electrodes implanted on human sensorimotor cortices. Some severely paralyzed patients due to stroke or trauma were shown to be able to operate the prosthetic arm only using their ECoG signals by imaging some movements of their paralyzed limbs. The patients operated the prosthetic arm to manipulate some objects by grasping and releasing. Furthermore, we have developed a prosthetic arm to be controlled by signals of magnetoencephalogram(MEG).

  • Research Products

    (18 results)

All 2012 2011 2010 Other

All Journal Article (5 results) Presentation (9 results) Book (1 results) Remarks (1 results) Patent(Industrial Property Rights) (2 results) (of which Overseas: 2 results)

  • [Journal Article] Electrocorticographic control of a prosthetic arm in paralyzed patients2012

    • Author(s)
      Yanagisawa T, Hirata M, Saitoh Y, Kishima H, Matsushita K, Goto T, Fukuma R, Yokoi H, Kamitani Y, Yoshimine T
    • Journal Title

      Annals of Neurology

      Volume: 71(3) Pages: 353-61

  • [Journal Article] Movement-related neuromagnetic fields and performances of single trial classifications2012

    • Author(s)
      Sugata H, Goto T, Hirata M, Yanagisawa T, Shayne M, Matsushita K, Yoshimine T, Yorifuji S
    • Journal Title

      Neuroreport

      Volume: 23(1) Pages: 16-20

  • [Journal Article] A fully-implantable wireless system for human brain-machine interfaces using brain surface electrodes : W-HERBS2011

    • Author(s)
      Hirata M, Matsushita K, Suzuki T, Yoshida T, Sato F, Morris S, Yanagisawa T, Goto T, Kawato M, Yoshimine T
    • Journal Title

      IEICE Trans Commun

      Volume: E94-B(9) Pages: 2448-2453

  • [Journal Article] Real-time control of a prosthetic hand using human electrocorticography signals2011

    • Author(s)
      Yanagisawa T, Hirata M, Saitoh Y, Goto T, Kishima H, Fukuma R, Yokoi H, Kamitani Y, Yoshimine T
    • Journal Title

      J Neurosurg

      Volume: 114(6) Pages: 1715-22

  • [Journal Article] Motor restoration based on the brain machine interface using brain surface electrodes : real time robot control and a fully-implantable wireless system

    • Author(s)
      Hirata M, Matsushita K, Yanagisawa T, Goto T, Morris S, Yokoi H, Suzuki T, Yoshida T, Sato F, Sakura O, Kamitani Y, Yoshimine T
    • Journal Title

      Advanced robotics

      Volume: (in press)

  • [Presentation] Gamma amplitude coupled with alpha phase represents motor2011

    • Author(s)
      Takufumi Yanagisawa
    • Organizer
      Society for neuroscience
    • Place of Presentation
      Washington DC convention center, USA
    • Year and Date
      2011-11-12
  • [Presentation] BMIによるロボットアーム制御と脳損傷後皮質脳波変化の定量的解析2011

    • Author(s)
      柳澤琢史
    • Organizer
      認知神経科学会学術集会
    • Place of Presentation
      産業医科大学、福岡
    • Year and Date
      2011-10-23
  • [Presentation] 脳損傷後の皮質脳波変化の定量的解析とBMIへの応用2011

    • Author(s)
      柳澤琢史
    • Organizer
      日本脳神経外科学会総会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2011-10-14
  • [Presentation] Gamma amplitude coupled with alpha phase represents motor2011

    • Author(s)
      柳澤琢史
    • Organizer
      日本神経科学学会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2011-09-17
  • [Presentation] 麻痺患者における感覚運動野皮質脳波の変化とBMIへの応用2011

    • Author(s)
      柳澤琢史
    • Organizer
      第50回日本定位・機能神経外科学会
    • Place of Presentation
      広島
    • Year and Date
      2011-01-22
  • [Presentation] Prosthetic arm control by paralyzed patients using neural decoding of their electrocorticograms2010

    • Author(s)
      Takufumi Yanagisawa
    • Organizer
      Society for neuroscience
    • Place of Presentation
      San diego, USA
    • Year and Date
      2010-11-13
  • [Presentation] 皮質脳波BMIを用いた麻痺患者の運動機能再建2010

    • Author(s)
      柳澤琢史
    • Organizer
      日本脳神経外科学会
    • Place of Presentation
      福岡国際会議場
    • Year and Date
      2010-10-29
  • [Presentation] Real-time and training-free control of a prosthetic arm using human2010

    • Author(s)
      Takufumi Yanagisawa
    • Organizer
      29^<th> ICCN
    • Place of Presentation
      Kobe
    • Year and Date
      2010-10-28
  • [Presentation] Prosthetic arm control by paralyzed patients using EGoG signals2010

    • Author(s)
      Takufumi Yanagisawa
    • Organizer
      Neuro2010
    • Place of Presentation
      Kobe
    • Year and Date
      2010-09-03
  • [Book] 皮質脳波を用いたBMIによる運動機能再建、先端医療シリーズ40リハ医とコメディカルのための最新リハビリテーション医学2010

    • Author(s)
      柳澤琢史平田雅之吉峰俊樹
    • Total Pages
      79-83
  • [Remarks] ホームページ

    • URL

      http://www.nsurg.med.osaka-u.ac.jp/school/research/research.html#c16

  • [Patent(Industrial Property Rights)] 体内埋込装置のケーシングと体内埋込装置、および体内埋込装置のケーシングの製造方法、および体内埋込装置を用いた治療支援方法2011

    • Inventor(s)
      平田雅之、吉峰俊樹、松下光次郎、後藤哲、柳澤琢史、鈴木隆文、吉村眞一
    • Industrial Property Rights Holder
      平田雅之、吉峰俊樹、松下光次郎、後藤哲、柳澤琢史、鈴木隆文、吉村眞一
    • Industrial Property Number
      PCT国際特許、PCT/ JP/ 2011/ 001402
    • Filing Date
      2011-03-10
    • Overseas
  • [Patent(Industrial Property Rights)] MACHINE CONTROL DEVICE, MACHINE SYSTEM, MACHINE CONTROL METHOD, AND RECORDING MEDIUM STORING MACHINE CONTROL PROGRAM2010

    • Inventor(s)
      Hirata M, Yanagisawa T, Kamitani Y, Yokoi H, Yoshimine T, Goto T, Fukuma R, Kato R
    • Industrial Property Rights Holder
      Hirata M, Yanagisawa T, Kamitani Y, Yokoi H, Yoshimine T, Goto T, Fukuma R, Kato R
    • Industrial Property Number
      米国特許、12/ 799, 840
    • Filing Date
      2010-05-03
    • Overseas

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Published: 2013-07-31  

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