2012 Fiscal Year Final Research Report
Design of artificial niche derived from functional proteins
| Project/Area Number |
22700468
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Biomedical engineering/Biological material science
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| Research Institution | University of Toyama (2011-2012)
Kyoto University (2010) |
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Principal Investigator |
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| Project Period (FY) |
2010 – 2012
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| Keywords | 人工臓器工学 / 再生医工学 / キメラタンパク質 / 幹細胞 |
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| Research Abstract |
I have been carried out the research for designing novel functional hydrogel incorporated with proteins for the protection and differentiation of transplanted cells. This hydrogel overcome the problems of “cell death with receiving damage from inflammatory response and an absence of adhesive scaffold” and “the defection of ability for strictly regulating differentiation in the host tissue”. In this study, I designed a collagen-based hydrogel possessing an ability for protection of transplanted cells and a biodegradable microparticles for strictly regulating the differentiation into dopaminergic neuron
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