2011 Fiscal Year Final Research Report
Development of Au-Ag nanorods for application of hyperthermic treatment
Project/Area Number |
22700479
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Single-year Grants |
Research Field |
Biomedical engineering/Biological material science
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Research Institution | Tokyo University of Science |
Principal Investigator |
KUTSUZAWA Koichi 東京理科大学, 総合研究機構, ポストドクトラル研究員 (90572066)
|
Project Period (FY) |
2010 – 2011
|
Keywords | ナノバイオロジー / ナノメディスン |
Research Abstract |
Nanotechnology is useful tools for various fields. In particular, nanomaterials have advantage in application of diagnostic, imaging tools and therapeutic tools. Gold nanomaterials, gold colloid and gold nanorods, now were focused on imaging tool of biotechnology and cancer therapy. We have researched polymer synthesis of bio-and chemical-functional materials and developed new dispersing agent to stabilize gold nanoparticles. This dispersing agent which PEG-g-Py Graft copolymer made from pyridine and poly(ethylene glycol)(PEG) as protein adsorption-resistant pendant chains was used to stabilize gold nanorods. Moreover gold nanorods have potential of photothermal conversion property. We developed Silver thin layer coated gold nanorods(PEG-g-Py coated Gold-Silver nanorods) to increase the photothermal conversion efficiency for cancer photothermal therapy. We researched new materials characterization of PEG-g-Py coated Gold-Silver nanorods. We confirmed that PEG-g-Py coated Gold-Silver nanordos could apply cancer photothermal therapy.
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Research Products
(7 results)