2011 Fiscal Year Final Research Report
Investigation of tissue regeneration by adipose tissues-derived cells ; Utilizing an imaging system
| Project/Area Number |
22700486
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Biomedical engineering/Biological material science
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| Research Institution | National Defense Medical College |
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Principal Investigator |
HATTORI Hidemi 防衛医科大学校, 防衛医学研究センター, 助教 (80508549)
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| Project Period (FY) |
2010 – 2011
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| Keywords | 脂肪組織由来間質細胞 / 骨髄細胞 / 炎症系細胞 / in vivoイメージング / ケモカイン / 血管新生 / 血管新生増殖因子 |
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| Research Abstract |
Adipose tissue is considered to be a useful cell source for cell-based therapy of ischemic disease. However, regeneration mechanism of tissue by adipose tissue-derived cell transplantation has not fully defined. In the present study, we examined about angiogenesis induced after adipose tissue derived-stromal cell transplantation by using an in vivo imaging system. From the results, it was suggested that the angiogenesis by adipose tissue derived-stromal cell transplantation was induced by the interaction between injected cells and migrated hematopoietic cells.
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