2011 Fiscal Year Final Research Report
Quantitative diagnosis method of liver diseases in consideration of fatty deposition
| Project/Area Number |
22700506
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Medical systems
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| Research Institution | Chiba University |
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Principal Investigator |
YAMAGUCHI Tadashi 千葉大学, フロンティアメディカル工学研究開発センター, 准教授 (40334172)
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| Project Period (FY) |
2010 – 2011
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| Keywords | 超音波 / 音響特性 / 生体物性 / 超音波顕微鏡 / 組織性状診断 / 定量診断 / 肝炎 |
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| Research Abstract |
The aim of this research is the realization of a quantitative diagnosis method of liver diseases using ultrasound. As a result of measuring and analyzing of physical and acoustic characteristics of rat livers using ultrasonic microscope systems, the correlation of tissue properties and various physical properties was confirmed. Moreover, the detection of the echo signal from fat and fiber tissues became possible, when some signal processing methods were given to echo data acquired at computer simulations, tissue mimicking phantoms, and clinical data sets using ultrasonic diagnostic equipment. The qualitative evaluation of the tissues in diffuse liver disease is actualized by fusion of both results.
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