2011 Fiscal Year Final Research Report
Effective resistance exercise method for muscle atrophy based on a cell biology
| Project/Area Number |
22700555
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Rehabilitation science/Welfare engineering
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| Research Institution | Nagoya Gakuin University |
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Principal Investigator |
ITOH Yuta 名古屋学院大学, リハビリテーション学部, 助手 (30454383)
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| Project Period (FY) |
2010 – 2011
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| Keywords | 筋萎縮 / 筋力増強運動 / 細胞生物学 |
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| Research Abstract |
Recovery from skeletal muscle atrophy by resistance exercise was examined in mice. After tail suspention, the animals were subjected to resistance exercise(RE). The myofiber thickness of soleus muscle of the mice with RE was significantly greater than that of non RE group, and was not significantly different from normal mice. Intriguingly, the number of myonuclei of the mice with RE was 1.5 times greater than that of non RE mice. We found that the newly-acquired myonuclei were increased within a few days after the onset of RE, suggesting that satellite cells proliferated rapidly after the onset of RE and fused to the myofibers.
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