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2011 Fiscal Year Final Research Report

Noninvasive monitoring of exercise induced microvascular expansion

Research Project

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Project/Area Number 22700702
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Applied health science
Research InstitutionTokyo Medical University

Principal Investigator

KIME Ryotaro  東京医科大学, 医学部, 講師 (90366120)

Co-Investigator(Renkei-kenkyūsha) NIWAYAMA Masatsugu  静岡大学, 工学部, 准教授 (40334958)
Project Period (FY) 2010 – 2011
Keywords運動性充血 / 近赤外線分光法 / 筋組織酸素動態 / 自転車運動 / 皮膚血流量
Research Abstract

We examined changes in total hemoglobin response during bicycle exercise at various constant workloads(f-Δ [tHb]) and clarified whether the f-Δ [tHb] indicates a dilation of the vascular bed and/or capillary recruitment or just an increase of skin blood flow.
The kinetics of f-Δ [tHb] was totally different from that of skin blood flow at all workloads, and the f-Δ [tHb] were significantly correlated with the increase of oxygenated hemoglobin(Δ [oxy]) during constant exercise. These results suggest that the increase of [tHb] during constant workloads may be caused by the microvasular expansion in muscle tissue.

  • Research Products

    (14 results)

All 2012 2011 2010 Other

All Journal Article (10 results) (of which Peer Reviewed: 9 results) Presentation (2 results) Book (2 results)

  • [Journal Article] 外側広筋の脱酸素化が高強度運動時に停滞する機序についての検討2012

    • Author(s)
      大澤拓也, 木目良太郎, 浜岡隆文, 山本正嘉, 勝村俊仁
    • Journal Title

      脈管学

      Volume: 52 Pages: 103-107

    • Peer Reviewed
  • [Journal Article] Attenuation of muscle deoxygenation precedes EMG threshold in normoxia and hypoxia2011

    • Author(s)
      Osawa T, Kime R, Hamaoka T, Katsumura T, Yamamoto M
    • Journal Title

      Med Sci Sports Exerc

      Volume: 43(8) Pages: 1406-13

    • Peer Reviewed
  • [Journal Article] Simultaneous determination of absorption coefficients for skin and muscle tissues using spatially resolved measurements2010

    • Author(s)
      Suzuki H, Niwayama M, Yamakawa T, Ohkubo M, Kime R, Katsumura T
    • Journal Title

      Advanced Materials Research

      Volume: 222 Pages: 309-312

    • Peer Reviewed
  • [Journal Article] Low-volume strength and endurance training prevent the decrease in exercise hyperemia induced by non-dominant forearm immobilization2010

    • Author(s)
      Ohmori F, Hamaoka T, Shiroishi K, Osada T, Murase N, Kurosawa Y, Ichimura S, Homma T, Esaki K, Kime R, Katsumura T
    • Journal Title

      Eur J Appl Physiol

      Volume: 110(4) Pages: 845-51

    • Peer Reviewed
  • [Journal Article] Unchanged muscle deoxygenation heterogeneity during bicycle exercise after 6 weeks of en-durance training2010

    • Author(s)
      Kime R, Niwayama M, Fujioka M, Shiroishi K, Osawa T, Shimomura K, Osada T, Murase N, Katsumura T
    • Journal Title

      Adv Exp Med Biol

      Volume: 662 Pages: 353-358

    • Peer Reviewed
  • [Journal Article] Comparison of muscle O_2 dynamics in different site of forearm flexor muscle during incremental handgrip exercise2010

    • Author(s)
      Fujioka M, Kime R, Koga S, Osawa T, Shimomura K, Osada T, Murase N, Katsumura T
    • Journal Title

      Adv Exp Med Biol

      Volume: 662 Pages: 359-64

    • Peer Reviewed
  • [Journal Article] Decreased muscle oxygenation and increased arterial blood flow in the nonexercising limb during leg exercise2010

    • Author(s)
      Shiroishi K, Kime R, Osada T, Murase N, Shimomura K, Katsumura T
    • Journal Title

      Adv Exp Med Biol

      Volume: 662 Pages: 379-84

    • Peer Reviewed
  • [Journal Article] Effects of acute hypoxia on the inflection point of muscle oxygenation2010

    • Author(s)
      Osawa T, Kime R, Katsumura T, Yamamoto M
    • Journal Title

      Adv Exp Med Biol

      Volume: 662 Pages: 385-90

    • Peer Reviewed
  • [Journal Article] 運動時血管機能の非侵襲的計測2010

    • Author(s)
      木目良太郎, 村瀬訓生, 勝村俊仁
    • Journal Title

      脈管学

      Volume: 50 Pages: 455-460

  • [Journal Article] Muscle oxygen saturation heterogeneity among leg muscles during ramp exercise

    • Author(s)
      Takagi S, Kime R, Niwayama M, Murase N, Katsumura T
    • Journal Title

      Adv. Exp. Med. Biol.

      Volume: (in press)

    • Peer Reviewed
  • [Presentation] NIRSを用いた末梢血管拡張機能の評価に及ぼす皮膚血流量の影響2011

    • Author(s)
      木目良太郎, 藤岡正子, 大澤拓也, 高木俊, 安生幹子, 金子泰久, 長田卓也, 村瀬訓生, 勝村俊仁
    • Organizer
      第66回日本体力医学会
    • Place of Presentation
      山口
    • Year and Date
      2011-09-17
  • [Presentation] 骨格筋NIRS評価指標の再検討.ワークショップ「体力医学分野での近赤外分光装置の応用」2011

    • Author(s)
      木目良太郎
    • Organizer
      第66回日本体力医学会
    • Place of Presentation
      山口
    • Year and Date
      2011-09-17
  • [Book] 筋エネルギー代謝,運動生理学のニューエビデンス2010

    • Author(s)
      木目良太郎
    • Total Pages
      259-267
    • Publisher
      真興交易
  • [Book] 肋間筋の酸素動態,身体運動と呼吸・循環機能

    • Author(s)
      木目良太郎, 大澤拓也
    • Publisher
      真興交易

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Published: 2013-07-31  

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