2012 Fiscal Year Final Research Report
Search for how to eat allergy-provoking foods to protect and cure of food allergy
| Project/Area Number |
22700765
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Eating habits, studies on eating habits
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| Research Institution | Nagoya University of Arts and Sciences |
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Principal Investigator |
YAMADA Chikako 名古屋学芸大学, 管理栄養学部, 講師 (30351216)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 食物アレルギー / リゾチーム / 免疫療法(減感作療法) |
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| Research Abstract |
We established the mouse model of immune therapy to food allergy with egg-white lysozyme. The mice were administrated different dose lysozyme, mixture with another constituent and chemically-modified lysozyme for therapy and analyzed symptoms induced after therapy. These mice showed shock symptoms but severity of them differed depending on the dose and form of the lysozyme. These results indicated that this mouse model is useful for evaluation of effect of immune therapy with the allergen itself.
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