2012 Fiscal Year Final Research Report
Morphological analysis of transcytosis mechanisms and FcRn expression
| Project/Area Number |
22700770
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Eating habits, studies on eating habits
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| Research Institution | University of Occupational and Environmental Health, Japan |
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Principal Investigator |
BABA Ryoko 産業医科大学, 医学部, 講師 (90271436)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 食物アレルギー / FcRn / 空腸 / 吸収上皮細胞 / トランスサイトーシス |
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| Research Abstract |
Transcytosis of macromolecules including maternal IgG occurs in the jejunal absorptive cells of newborn and suckling mice. However, transcytosis disappeared after weaning. The transport system was mediated by neonatal Fc receptor (FcRn). The pattern of gene expression was varied among suckling and adult, proximal and distal small intestine.
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[Journal Article] An integrin-activating peptide, PHSRN, ameliorates inhibitory effects of conventional peritoneal dialysis fluids on peritoneal wound healing2010
Author(s)
Miyamoto T, Tamura M, Kabashima N, Serino R, Shibata T, Furuno Y, Miyazaki M, Baba R, Sato N, Doi Y, Okazaki M, Otsuji Y
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Journal Title
Nephrology, Dialysis, Transplantation
Volume: 25(4)
Pages: 1109-1119
DOI
Peer Reviewed
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[Presentation] High glucose peritoneal dialysate induce apoptosis through endoplasmic reticulum stress in peritoneal mesothelial cells2012
Author(s)
Nakamata J, Morimoto H, Baba R, Ishimatsu N, Miyamoto T, Kanegae K, Serino R, Kabashima N, Otsuji Y, Doi Y, Tamura M
Organizer
49th ERA-EDTA (European Renal Association- European Dialysis and Transplant Association) Congress
Place of Presentation
Paris(France)
Year and Date
20120524-27
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[Presentation] Pentraxin 3 Expression in a Rat Model of Continuous Peritoneal Dialysis2012
Author(s)
Ishimatsu N, Miyamoto T, Morimoto H, Nakamata J, Baba R, Kanegae K, Serino R, Kabashima N, Otsuji Y, Doi Y, Tamura M
Organizer
49th ERA-EDTA (European Renal Association - European Dialysis and Transplant Association) Congress
Place of Presentation
Paris(France)
Year and Date
20120524-27
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[Presentation] High glucose levels induce endoplasmic reticulum stress in peritoneal mesothelial cells2010
Author(s)
Nakamata J, Morimoto H, Baba R, Miyamoto T, Shibata T, Serino R, Kabashima N, Otsuji Y, Doi Y, Tamura M
Organizer
43rd Annual Meeting & Scientific Exposition (American Society of Nephrology, Renal week 2010)
Place of Presentation
Denver(USA)
Year and Date
20101116-21
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