2011 Fiscal Year Final Research Report
Diet, genes, and breast cancer risk in case-control studies in Japanese, Japanese Brazilians, and non-Japanese Brazilians
| Project/Area Number |
22700934
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Cancer epidemiology and prevention
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| Research Institution | National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East |
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Principal Investigator |
IWASAKI Motoki 独立行政法人国立がん研究センター, がん予防・検診研究センター, 室長 (60392338)
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| Co-Investigator(Renkei-kenkyūsha) |
HAMADA Gerson shigueaki Nikkei Disease Prevention Center, Director
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| Project Period (FY) |
2010 – 2011
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| Keywords | 遺伝子環境交互作用 / 日系移民 |
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| Research Abstract |
We examined the association between green tea, calcium, vitamin D intake and the risk of breast cancer in case-control studies in Nagano and Sao Paulo. We further investigated gene-environment interaction using genetic polymorphisms related to these dietary factors. No significant association was found between green tea consumption and breast cancer risk and no significant interaction was observed by potential genetic effect modifiers. An inverse association was suggested between calcium and vitamin D intake, and breast cancer risk. We have investigated gene-environment interaction using genetic polymorphisms related to vitamin D receptor gene and blood level of vitamin D.
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Research Products
(17 results)
