2011 Fiscal Year Final Research Report
Development of Size Exclusion Chromatography coupled with Small Angle X-ray Scattering(SEC-SAXS) for simultaneous measurement of size, molar mass, and shape of nano-particles
| Project/Area Number |
22710109
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Nanomaterials/Nanobioscience
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| Research Institution | The Institute of Physical and Chemical Research |
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Principal Investigator |
TAKEMASA Makoto 独立行政法人理化学研究所, 前田バイオ工学研究室, 基礎科学特別研究員 (30318795)
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| Project Period (FY) |
2010 – 2011
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| Keywords | 希薄溶液物性 / 回転半径 / X線小角散乱 / 放射光 / HPLC / SEC-MALLS |
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| Research Abstract |
Radius of gyration can be estimated only for molecules or particles with sizes larger than 10～ 20nm using widely used light scattering instruments, although the characterization of nano-sized particles and polymers is quite essential both for fundamental science and application. We developed SEC-SAXS(Size Exclusion Chromatography coupled with Small Angle X-ray Scattering) using a flow cell, and investigate dilute solution properties of water soluble polymers.
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