2011 Fiscal Year Final Research Report
Development of a cell microarray chip device for diagnosis of infectious disease
| Project/Area Number |
22710124
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Microdevices/Nanodevices
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| Research Institution | National Institute of Advanced Industrial Science and Technology |
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Principal Investigator |
YAMAMURA Shohei 独立行政法人産業技術総合研究所, 健康工学研究部門, 研究員 (50432141)
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| Project Period (FY) |
2010 – 2011
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| Keywords | 細胞チップ / マイクロアレイ / バイオチップ / 単一細胞解析 / ハイスループットスクリーニング / 感染症 / マラリア |
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| Research Abstract |
Malaria is a vector-borne infectious disease caused by protozoan parasites. There are approximately 500 million cases of malaria, killing over two million people each year. The most standard detection method ; Giemsa-stained blood smears to detect malaria parasite in erythrocytes is time-consuming and need to technical handling. Although the detection methods based on immunochromatography and PCR were developed, they also have some problems in sensitivity and rapidity. In this study, we have developed a novel cell microarray system to detect malaria-infected erythrocytes with the high-sensitivity(<0.0001%) in a short time.
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