2011 Fiscal Year Final Research Report
Asymmetric Synthesis of Chiral Organosilicon Compounds and Their Applications
| Project/Area Number |
22750042
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Organic chemistry
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| Research Institution | Kyushu University |
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Principal Investigator |
IGAWA Kazunobu 九州大学, 先導物質化学研究所, 助教 (80401529)
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| Project Period (FY) |
2010 – 2011
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| Keywords | 有機元素化学 / 不斉合成 / キラルケイ素化合物 |
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| Research Abstract |
To efficiently approach non-racemic chiral organosilicon compounds, a novel reactive silane, which can react with nucleophiles in a stereospecific manner, and an oxidative cleavage reaction of C-Si bond with ozone have been developed. These new reactions allow to obtain a silicon congener of a-hydroxy carboxylic acid derivatives, which are difficult to obtain by other methods.
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