2012 Fiscal Year Final Research Report
Development of Environmentally Benign Selective Oxidation Reactions Using Designer Hypervalent Iodine Catalysts
Project/Area Number |
22750087
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Single-year Grants |
Research Field |
Synthetic chemistry
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Research Institution | Nagoya University |
Principal Investigator |
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Project Period (FY) |
2010 – 2012
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Keywords | 選択的合成・反応 |
Research Abstract |
In this study, we achieved several oxidation reactions using designer hypervalent iodine catalysts. We have developed the first example of the organoiodine(V)-catalyzed regioselective oxidation of phenols to ortho-quinones using 2-iodoxybenzenesulfonic acid (IBS). Moreover, we succeeded in the rational design of conformationally flexible iodosylarenes based on secondary nonbonding interactions as chiral catalysts for the enantioselective oxidative dearomatization of 1-naphthols. Furthermore, we have developed the intra- and intermolecular direct x-oxyacylation reactions of carbonyl compounds catalyzed by in situ-generated ammonium (hypo)iodite species with hydrogen peroxide or TBHP as an environmentally benign oxidant
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