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2011 Fiscal Year Final Research Report

Plasma separation chip driven by capillary force

Research Project

  • PDF
Project/Area Number 22760104
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Production engineering/Processing studies
Research InstitutionRitsumeikan University

Principal Investigator

SAKAMOTO Hiroaki  立命館大学, 総合理工学研究機構, ポストドクトラルフェロー (70552454)

Project Period (FY) 2010 – 2011
Keywords血漿分離 / マイクロ流路 / 微細加工 / マイクロTAS / 電気化学 / 血液検査 / 表面処理
Research Abstract

In this study, a microdevice driven by capillary action has been developed for the high-throughput on-chip separation of plasma from a drop of blood. In order to separate plasma from blood, we designed 2μm deep array channels to filter the red blood cells. After injection of a blood sample, the plasma flowed rapidly and arrived at the outlet within 3 min, demonstrating a 100% separation ratio of red blood cells. Because the proposed blood separation device is driven solely by capillary action, it is possible to miniaturize it as an entire system.

  • Research Products

    (7 results)

All 2012 2011 2010

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (5 results)

  • [Journal Article] Plasma separation PMMA device driven by capillary force controlling surface wettability2012

    • Author(s)
      Hiroaki Sakamoto, Ranko Hatsuda, Kazuhiro Miyamura, and Susumu Sugiyama
    • Journal Title

      Micro & Nano Letters

      Volume: 7 Pages: 64-67

    • Peer Reviewed
  • [Journal Article] Electrochemical Selective Detection of Uric Acid Using a Copper-modified Carbon Electrode2011

    • Author(s)
      Hiroaki Sakamoto, Ranko Hatsuda, Kazuhiro Miyamura, Haruki Shiraishi and Susumu Sugiyama
    • Journal Title

      Analytical Science

      Volume: 27 Pages: 333-335

    • Peer Reviewed
  • [Presentation] 電気化学計測を行うマイクロ流路の最適な構造設計2011

    • Author(s)
      坂元博昭、初田蘭子、宮村和宏、白石晴樹、杉山進
    • Organizer
      第28回センサ・マイクロマシンと応用システム
    • Place of Presentation
      タワーホール船堀東京都
    • Year and Date
      2011-09-26
  • [Presentation] Blood plasma separation PMMA device using capillary phenomenon and its application for Point Of Care Testing device2010

    • Author(s)
      Hiroaki SAKAMOTO, Ranko HATSUDA, Kazuhiro MIYAMURA, Haruki SHIRAISHI and Susumu SUGIYAMA
    • Organizer
      Pacifichem2010, 18^<th>
    • Place of Presentation
      Hawaii, U. S. A.
    • Year and Date
      2010-12-18
  • [Presentation] Design and fabrication blood plasma PMMA chip using capillary phenomenon2010

    • Author(s)
      Hiroaki SAKAMOTO, Ranko HATSUDA, Kazuhiro MIYAMURA, Haruki SHIRAISHI and Susumu SUGIYAMA
    • Organizer
      2010 Int' l Symposium on Micro-NanoMechatronics and Human Science & Micro-Nano Global COE(MHS2010), 8^<th>
    • Place of Presentation
      愛知県
    • Year and Date
      2010-10-08
  • [Presentation] 銅修飾カーボン電極による尿酸の選択的検出2010

    • Author(s)
      坂元博昭、初田蘭子、宮村和宏、白石晴樹、杉山進
    • Organizer
      日本分析化学会第59年会
    • Place of Presentation
      東北大学宮城県
    • Year and Date
      2010-09-17
  • [Presentation] 血漿分離、スクリーニング、検出を集積したオンサイト型血液診断装置の開発2010

    • Author(s)
      坂元博昭、初田蘭子、宮村和宏、白石晴樹、杉山進
    • Organizer
      第20回マイクロエレクトロニクスシンポジウム
    • Place of Presentation
      立命館大学滋賀県
    • Year and Date
      2010-09-10

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Published: 2013-07-31  

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