2011 Fiscal Year Final Research Report
Development of novel cell-based assay chip using microfluidics
| Project/Area Number |
22760618
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Biofunction/Bioprocess
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| Research Institution | National Institute of Advanced Industrial Science and Technology |
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Principal Investigator |
SUGIURA Shinji 独立行政法人産業技術総合研究所, 幹細胞工学研究センター, 主任研究員 (10399496)
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| Project Period (FY) |
2010 – 2011
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| Keywords | 医用化学工学 |
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| Research Abstract |
We developed a perfusion culture microchamber array chip with a serial dilution microfluidic network for analyzing drug dose response, which is required for practical drug discovery applications. We used a mathematical model of transport phenomena to investigate the concentration profile of oxygen and substances in a perfusion cell-culture microchamber array, and obtained optimal design strategy of a microfluidic perfusion culture chip.
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[Presentation] Integrated Pressure Driven Perfusion Culture Microchamber Array Chip For High-Throughput Drug Dose Response Assay2010
Author(s)
Sugiura, S., Hattori, K., Fujihashi, M., Kurokawa, M., Nakano, Y., Yanagisawa, M., & Kanamori, T.
Organizer
The International Symposium on Microchemistry and Microsystems(ISMM) 2010
Place of Presentation
Hong Kong
Year and Date
2010-05-28
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