2011 Fiscal Year Final Research Report
Elucidation of mechanisms of selective peroxisome degradation using an ubiquitin-like autophagy protein
Project/Area Number |
22770049
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Single-year Grants |
Research Field |
Plant molecular biology/Plant physiology
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Research Institution | The Institute of Physical and Chemical Research |
Principal Investigator |
YOSHIMOTO Koki 独立行政法人理化学研究所, 植物免疫研究グループ, 研究員 (40399316)
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Project Period (FY) |
2010 – 2011
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Keywords | オートファジー / 液胞 / オルガネラ / ペルオキシソーム / 細胞内自己分解 / 品質管理 |
Research Abstract |
Autophagy is the major system responsible for the degradation of organelles and cytosolic macromolecules in the vacuole. I found that dysfunctional peroxisomes were highly accumulated in leaves of autophagy-defective mutants, indicating that autophagy is involved in quality control of leaf peroxisomes in plants. I also tried to elucidate molecular mechanisms for selective peroxisome degradation in Arabidopsis.
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[Journal Article] The Rab GTPase RabG3b functions in autophagy and contributes to tracheary element differentiation in Arabidopsis2010
Author(s)
Kwon, S. I., Cho, H. J., Jung, J. H., Yoshimoto, K., Shirasu, K., and Park, O.
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Journal Title
Plant J.
Volume: 64
Pages: 151-164
Peer Reviewed
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