2011 Fiscal Year Final Research Report
Analysis of a mechanism of regulation of bacterial cell shape by a novel protein RodZ
| Project/Area Number |
22770179
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Molecular biology
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| Research Institution | National Institute of Genetics |
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Principal Investigator |
SHIOMI Daisuke 国立遺伝学研究所, 系統生物研究センター, 特任研究員 (70507532)
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| Project Period (FY) |
2010 – 2011
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| Keywords | 細胞形態 / 細胞骨格 / 細胞長 / 細胞幅 / 極性 / 大腸菌 |
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| Research Abstract |
I have shown that a novel protein RodZ colocalizes with MreB, a bacterial actin, and forms spirals along the long axis of the cell. Thus, we think that RodZ along with MreB regulates the cell length. I found in this study that RodZ localizes at midcell dependently on MreB and FtsZ, a bacterial tubulin. Cells producing RodZ which cannot localize at midcell are wider that cells producing WT RodZ, suggesting that RodZ regulates the cell width as well as the cell length.
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