2011 Fiscal Year Final Research Report
Functional analysis of signaling molecules regulating fate decision of epidermis and neural tissue in embryonic ectoderm
| Project/Area Number |
22770211
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Developmental biology
|
|---|
| Research Institution | Kyoto University |
|---|
Principal Investigator |
KUSAKABE Morioh 京都大学, 大学院・生命科学研究科, 助教 (80378843)
|
|---|
| Project Period (FY) |
2010 – 2011
|
| Keywords | シグナル伝達 / 発生・分化 |
|---|
| Research Abstract |
In vertebrates, embryonic ectoderm is fated to give rise to epidermis or neural tissue. We have shown that a novel one-pass transmembrane protein EIG121L promotes epidermal differentiation of Xenopus embryonic ectoderm. Our analyses also suggested that EIG121L binds to BMP receptors and has a positive role in BMP signaling during epidermal differentiation.
|
Research Products
(9 results)
