2011 Fiscal Year Final Research Report
An Evo-Devo study for mechanisms of early embryogenesis in vertebrates
| Project/Area Number |
22770229
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Developmental biology
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| Research Institution | The Institute of Physical and Chemical Research |
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Principal Investigator |
TAKEUCHI Masaki 独立行政法人理化学研究所, ボディプラン研究グループ, 専門職研究員 (00392019)
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| Project Period (FY) |
2010 – 2011
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| Keywords | 体軸 / オーガナイザー / 三胚葉 / 条鰭類 / 両生類 / siamois / Wntシグナル / nodal |
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| Research Abstract |
Xenopus siamois is a homeobox gene cording for a transcriptional mediator of the dorsal Wnt signaling pathway and is necessary for the head formation. Despite its importance in Xenopus development, no siamois-related genes have been found in other taxa. In this study, I found a novel siamois-related gene, dioskouroi, in bichir. The bichir gene, which is different from siamois, plays roles in not only organizer formation but also endoderm differentiation endogenously. These results lead to a hypothesis that the siamois-related protogene in a common ancestor of bony fishes played central role in early embryogenesis.
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Research Products
(13 results)
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[Journal Article] Overview of the transcriptome profiles identified in hagfish, shark, and bichir : current issues arising from some nonmodel vertebrate taxa2011
Author(s)
Takechi M., Takeuchi M., Ota K. G., Nishimura O., Mochii M., Itomi K., Adachi1 N., TakahashiM., Fujimoto S., Tarui H., Okabe M., Aizawa S., Kuratani S.
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Journal Title
Journal of Experimental Zoology Part B : Molecular and Developmental Evolution
Volume: 316B
Pages: 526-546
Peer Reviewed
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