2011 Fiscal Year Final Research Report
Molecular and developmental genetics of metamorphosis in fish
| Project/Area Number |
22780170
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
General fisheries
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| Research Institution | Tohoku University |
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Principal Investigator |
YOKOI Hayato 東北大学, 大学院・農学研究科, 助教 (40569729)
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| Project Period (FY) |
2010 – 2011
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| Keywords | 変態 / 発生 / 小型魚類 / モデル生物 |
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| Research Abstract |
This study aimed to accumulate the basic scientific knowledge on the metamorphosis in fish to help establishing more efficient production of the flounder aquaculture which has a huge economical impact in Japan. I conducted molecular and developmental genetic studies using medaka as a model. GFP transgenic lines were generated in order to monitor in vivo thyroid hormone level in a live fish. In another approach to establish medaka as a model system for studying metamorphosis, approximately 20 candidate marker genes that are implicated in thyroid grand development and/or thyroid hormone signaling were cloned and their embryonic expression patterns were examined.
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