2011 Fiscal Year Final Research Report
Clarification of local GnRH-induced luteolysis in the rat ovaryand challenge to control thecorpus luteumlife span
| Project/Area Number |
22780263
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Basic veterinary science/Basic zootechnical science
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| Research Institution | Kitasato University |
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Principal Investigator |
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| Project Period (FY) |
2010 – 2011
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| Keywords | ゴナドトロピン放出ホルモン / アネキシンA5 / 黄体退行 / メタスチン / アポトーシス / 卵巣 / 性周期 / エストロジェン |
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| Research Abstract |
Thecorpusluteum regresses rapidlyif prolactin is not adequately supplied until the afternoon on diestrus 2.In this study, we focused onthemechanisms of time-specific determinationof thecorpus luteum life span in rats. Eventually, we clarified that1) local gonadotropin-releasing hormone could alter the expression ratio of prolactin receptor isoforms in corpus luteum, and 2) we could control theduration of luteal phase by changing that expression ratioartificially.
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Research Products
(38 results)
