2011 Fiscal Year Final Research Report
MicroRNA expression in the canine tumor
| Project/Area Number |
22780283
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Clinical veterinary science
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| Research Institution | Kagoshima University |
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Principal Investigator |
MIURA Naoki 鹿児島大学, 農学部, 准教授 (80508036)
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| Project Period (FY) |
2010 – 2011
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| Keywords | イヌ / microRNA / 腫瘍 / 疾患マーカー |
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| Research Abstract |
A few novel microRNAs, which was up-or down-regulated in either mammary gland tumor or melanoma, were identified by the canine micro RNA microarray. The differential expression of these microRNAs was confirmed by quantitative RT-PCR. We also found that miR-21 and miR-92a had been significantly higher existing in the plasma from dog with mammary gland tumor compared to clinically healthy dog.
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