2012 Fiscal Year Final Research Report
Development of new synthetic reactions based on novel acid catalysts
| Project/Area Number |
22790019
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Chemical pharmacy
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| Research Institution | Tokyo University of Pharmacy and Life Science |
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Principal Investigator |
YANAI Hikaru 東京薬科大学, 薬学部, 助教 (10408685)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 触媒開発 / ブレンステッド酸 / ルイス酸 / 多成分反応 |
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| Research Abstract |
Synthetic organic chemistry plays an important role to develop functional chemicals. In this research, to improve the efficiency of chemical synthesis, we successfully developed highly effective acid catalyst containing C-H acid functionality. The carbon acid can be used as one of the most effective catalysts in some reactions using silicon enolates. Furthermore, we found that In(OTf)3 nicely catalyzes novel isocyanide-based multi component reactions.
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