2011 Fiscal Year Final Research Report
Ring-opening functionalizations of heterocycles to highly substituted compounds
| Project/Area Number |
22790025
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Chemical pharmacy
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| Research Institution | Gifu Pharmaceutical University |
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Principal Investigator |
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| Project Period (FY) |
2010 – 2011
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| Keywords | 有機化学 / 触媒 / ヘテロ環 / 開環反応 |
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| Research Abstract |
Ring-opening functionalizations of heterocycles are important and challenging to efficiently synthesize highly-substituted basic skeletones of functional materials. We have established C-C or C-N bond formations accompanying with ring-opening of tetra-or dihydrofurans, thermodynamically stable ring systems and the condensed-ring derivatives forming unstable cation intermediates to afford highly functionalized linear and cyclic products. The present methods are applicable to prepare the versatile bioactive and functional materials.
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