2012 Fiscal Year Final Research Report
Analysis ofinositolphospholipid signaling pathway in fission yeast
| Project/Area Number |
22790093
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Biological pharmacy
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| Research Institution | Kinki University |
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Principal Investigator |
KITA Ayako 近畿大学, 薬学部, 助教 (00388498)
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| Project Period (FY) |
2010 – 2012
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| Keywords | イノシトールリン脂質経路 / 細胞内輸送 / 分裂酵母モデル生物 / クラスリンアダプター複合体 / 低分子量Gタンパク質 / カルシニューリン / 免疫抑制薬 |
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| Research Abstract |
This project aims to identify regulatory factors of lipid metabolismthereby elucidating their physiological functions in fission yeast. We identified regulators of inositol phospholipid signaling pathway and membrane trafficking pathway, and demonstrated novel membrane trafficking mechanism. We also obtained interesting observations regarding the relationship between inositol phospholipid signaling pathwayand membrane trafficking pathway.
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[Journal Article] Sip1, a Conserved AP-1 Accessory Protein, is Important for Golgi/Endosome Trafficking in Fission Yeast.2012
Author(s)
Yu Y, Kita A, Udo M, Katayama Y, Shintani M, Park K, Hagihara K, Umeda N, Sugiura R.
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Journal Title
PLoS ONE
Volume: 7(9)
Pages: e45324
DOI
Peer Reviewed
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[Journal Article] Roel of the RNA-binding Protein Nrd1 in Stress Granule Formation and Its Implication in the Stress Response in Fission Yeast2012
Author(s)
Satoh R, Tanaka A, Kita A, Morita T, Matsumura Y, Umeda N, Takada M, Hayashi S, Tani T, Shinmyozu K, Sugiura R.
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Journal Title
PLoS ONE
Volume: 7(1)
Pages: e29683
DOI
Peer Reviewed
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