2012 Fiscal Year Final Research Report
Novel modification method of oligonucleotides for siRNA medicine
| Project/Area Number |
22790107
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Drug development chemistry
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| Research Institution | Gifu University |
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Principal Investigator |
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| Research Collaborator |
KITADE Yukio 岐阜大学, 工学部, 教授 (20137061)
UENO Yoshihito 岐阜大学, 応用生物科学部, 教授 (20250467)
IKEDA Masato 岐阜大学, 工学部, 准教授 (20432867)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 核酸医薬 / siRNA / オリゴ核酸修飾 |
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| Research Abstract |
Small interfering RNAs (siRNAs) are considered to be attractive candidates as nucleic acid drugs, owing to their powerful regulation of gene expression in a sequence-specific manner. In this study, novel some solid supports and synthetic method of artificial nucleic acids for chemically modified siRNA were developed.
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Research Products
(5 results)
