2012 Fiscal Year Final Research Report
Evaluation of bioactive peptide kisspeptin as a biomarker
| Project/Area Number |
22790172
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Medical pharmacy
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| Research Institution | Tokyo University of Pharmacy and Life Science |
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Principal Investigator |
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| Project Period (FY) |
2010 – 2012
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| Keywords | ペプチド / バイオマーカー / がん / 性腺機能低下症 / 周産期疾患 |
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| Research Abstract |
Kisspeptin is a bioactive peptide, which has been suggested to relate with cancers, hypogonadism, and perinatal disease. The author developed a sensitive enzyme immunoassay , which could measure blood kisspeptin concentrations, and tried to we identify diagnosable disease by plasma kisspeptin levels as a biomarker. Measuring and analysis of plasma/serum kisspeptin levels in healthy subjects and patients suggests that plasma kispeptin levels are expected to be a good biomarker for perinatal complication.
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