2011 Fiscal Year Final Research Report
The role of cellular prion protein in blood brain barrier
| Project/Area Number |
22790178
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Medical pharmacy
|
|---|
| Research Institution | Fukuoka University |
|---|
Principal Investigator |
|
|---|
| Project Period (FY) |
2010 – 2011
|
| Keywords | 薬物動態 / 代謝学 |
|---|
| Research Abstract |
This study aimed to address the role of cellular prion protein(PrPC) in amyloid-beta(Aβ) efflux via blood brain barrier. PrPC knockdown did not affect Aβ transport although other transporters(low density lipoprotein related protein 1 and P-glycoprotein) changed Aβ transport.
|
