2012 Fiscal Year Final Research Report
Architecture of top-down signals conveyed toward extrastriate cortex revealed by rabies virus in the macaque monkey.
| Project/Area Number |
22790202
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
General physiology
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| Research Institution | The University of Tokyo |
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Principal Investigator |
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| Project Period (FY) |
2010 – 2012
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| Keywords | 大脳視覚野 / 狂犬病ウイルス / マカクサル |
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| Research Abstract |
We investigated the architecture of multi-synaptic top-down pathways toward visual area4 (V4) of ventral stream and visual area 5 (MT/V5) of dorsal stream, employing retrograde trans-synaptic transport of rabies virus. In addition, multi-synaptic architecture from the medial temporal lobe to V4 was also investigated. We found that frontal inputs to MT/V5 and V4 mainly arise from area 46v. In addition, we found shot-cut pathway from the hippocampus proper to V4. These results indicate that multi-synaptic architecture may provide top-down information about object recognition accomplished throughoccipito-temporal and occipito-parietal pathways.
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