2011 Fiscal Year Final Research Report
Clarification of the mechanism of a novel inhibitory effect on platelet aggregation via prostaglandin E_2 receptor
| Project/Area Number |
22790241
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
General pharmacology
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| Research Institution | Asahikawa Medical College |
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Principal Investigator |
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| Project Period (FY) |
2010 – 2011
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| Keywords | 心血管 / 血液 |
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| Research Abstract |
In this study, it was suggested that selective activation of prostaglandin E_2 receptor subtype EP_2 or EP4 showed the inhibitory effect on platelet aggregation. Notably, an EP_4 agonist can inhibit human platelet aggregation with high potency, suggesting a potential of EP_4 agonists as novel anti-platelet agents.
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Research Products
(6 results)
