2011 Fiscal Year Final Research Report
Antipsychotic potential of antioxidative agents in animal model for schizophrenia
| Project/Area Number |
22790245
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
General pharmacology
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| Research Institution | Niigata University |
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Principal Investigator |
MIZUNO Makoto 新潟大学, 脳研究所, 特任准教授 (20345515)
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| Project Period (FY) |
2010 – 2011
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| Keywords | 栄養因子 / 活性酸素 / ドパミン / 認知 / 統合失調症 |
|---|
| Research Abstract |
We established the model for schizophrenia and examined the antipsychotic actions of antioxidants. Administration of antioxidants for a week significantly ameliorated deficits of social interaction and prepulse inhibition of the schizophrenia model rats. These results suggest that antioxidants may be a new class of antipsychotic drugs for schizophrenia.
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Research Products
(6 results)
