2012 Fiscal Year Final Research Report
Establishment of isolation of amnion derived stem cells
| Project/Area Number |
22790277
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
General medical chemistry
|
|---|
| Research Institution | University of Toyama |
|---|
Principal Investigator |
KOIKE Chika 富山大学, 大学院・医学薬学研究部(医学), 助教 (10523889)
|
|---|
| Project Period (FY) |
2010 – 2012
|
| Keywords | 再生医学 |
|---|
| Research Abstract |
The stemness gene expression of human amnion epithelial cells （HAE) and mesenchymal cells （HAM) was compared with that of iPS cells and bone marrow derived mesenchymal stem cells （BMMSC), and was higher than BMMSC. It was suggested that HAE and HAM are closer to iPS cells than BMMSC. Drug treatment and Oct3/4 gene introduction into HAE cells made their stemness gene expression increased. Stem cells in HAE cells could be isolated according to TRA1-60 expression. HAM cells may have different differentiation potency according to their cell size.
|
-
-
-
-
-
-
-
-
-
-
-
-
-
-
[Presentation] Characterization of Amniotic Stem Cells2010
Author(s)
Chika Koike, Kaixuan Zho, Moustafa Fathy, Motonori Okabe, Toshiko Yoshida, and Toshio NIkaido.他
Organizer
The 8thInternational Society for Stem Cell Research
Place of Presentation
San Francisco, CA, U.S.A
Year and Date
2010-06-18
-
-
