2011 Fiscal Year Final Research Report
Investigation of relationship between gastric carcinogenesis in the young patients and intracellular oxidative stress induced by H. pylori infection
| Project/Area Number |
22790345
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Human pathology
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| Research Institution | Kyushu University |
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Principal Investigator |
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| Project Period (FY) |
2010 – 2011
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| Keywords | 胃癌発癌 / H.ピロリ菌 / 慢性炎症 / 活性酸素 / 病理学 / 8 hydroxy 2 / deoxyguanosne(8OHIG) / peroxiredoxin(PRDX) |
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| Research Abstract |
Although Helicobacter pylori(H. pylori)-i nfected chronic gastritis is described as accumulating reactive oxygen species(thinthe gastric epithelial cells and as relatingto the carcimgenesis, the further relationshiprenaiins to be conpletely elucidated. Inthis study, ve i nvesti gated the expression of RE relating substances in the gastric cancer and noncancerous gastric nuacosa, and conpared the expressi on i n gastritis, to difference young that patients, under 30 years of age, innot-young pat i ents, nmre than between the two groups. coexisting 40 years of H. age. pyrol 1-i of eat ed W found son
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