2012 Fiscal Year Final Research Report
The analysis for association of the polymorphisms of Stx prophage and host genome sequences in the production of Vero-toxin of enterohemorrhagic Echerichia coli
| Project/Area Number |
22790424
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Bacteriology (including Mycology)
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| Research Institution | Toyama Institute of Health |
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Principal Investigator |
KIMATA Keiko 富山県衛生研究所, 細菌部, 主任研究員 (50360805)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 細菌 / 大腸菌 / 感染症 |
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| Research Abstract |
This study was performed to analyze the polymorphic sequences of the downstream regions of stx2 or stx2c in enterohemorrhagic Escherichia coli (EHEC). By the phylogenic analysis, the polymorphic sequences of stx2c downstream regions were clustered in two groups without stx genotypes or serotype. The polymorphic sequences in stx2-downstream regions showed 3 clusters, one cluster with only O157 and the other clusters with main non-O157. The association was found between the polymorphic sequences in stx2-downstream regions and the host serotypes.
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