2012 Fiscal Year Final Research Report
The individualization of breast cancer by stem cell properties and search of new marker for classification
| Project/Area Number |
22790520
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Laboratory medicine
|
|---|
| Research Institution | Tohoku University |
|---|
Principal Investigator |
ITO Takako 東北大学, 大学院・医学系研究科, 助教 (10375173)
|
|---|
| Project Period (FY) |
2010 – 2012
|
| Keywords | 腫瘍検査学 / 乳癌 / 幹細胞 / 個別化 |
|---|
| Research Abstract |
In this study, the relation between stemness properties of spheroids prepared from primary breast cancers and clinicopathological findings was investigated. Luminal breast cancer could be separated into two subclasses by stemness-related gene expression, and NANGO-high type was predicted to be high stemness properties and high grade tumors. This classification could be useful and a novel criterion for subclassification of luminal breast cancers.
|
